Finally, Coronavirus cure found in Isreal with 100% survival rate
Israeli-based Pluristem has treated its first American patient suffering from COVID-19 complications under the country’s compassionate use program, reports the Jerusalem Post.
The success story has sparked widespread jubilation in Isreal, the United States and Europe with hope that accelerated manufacturing could see patients treated in what appears to be battles against a dangerous virus.
The success news comes days after a report by the company showed that six critically ill coronavirus patients in Israel who are considered high-risk for mortality were treated with Pluristem’s placenta-based cell-therapy product and survived, according to preliminary data provided by the Haifa-based company.
In the US case, the patient was treated with the company’s PLX cell therapy at Holy Name Medical Center in New Jersey, where Pluristem is already running a Phase III critical limb ischemia study. Like the patients treated in Israel, this patient was critically ill with respiratory failure due to acute respiratory distress syndrome and was intubated in an intensive care unit for three weeks.
The company’s president and CEO, Yaky Yanay, said that although Pluristem is focused on a planned multinational clinical trial for the treatment of complications associated with coronavirus, it does hope to expand treatment under compassionate use in other countries at the same time.
Not only had all the patients survived one week later, according to Pluristem, but four of them showed improvement in respiratory parameters and three of them are in the advanced stages of weaning from ventilators. Moreover, two of the patients with preexisting medical conditions are showing clinical recovery in addition to the respiratory improvement.
Shortly after the preliminary data was published, Dr. Jason McCarthy, a senior managing director covering the biotechnology industry at Maxim Group praised Pluristem’s efforts: “Pluristem shows the COVID-19 world the first clinical data for stem cells,” he wrote. “Pluristem is initially evaluating its cell therapy under compassionate use authorization in Israel and is also the first company to dose COVID-19 patients, as well as produce the first set of early stage data.”
The company’s results were described by Yahoo! Finance as “promising to say the least.”
“Weighing in for H.C. Wainwright, analyst Swayampakula Ramakanth calls the early data ‘encouraging’ and thinks the treatment could drive substantial gains for PSTI,” the Yahoo! Finance article reported.
PSTI is the company’s NASDAQ listing.